LONDON (AP) — Buffalo Bills starting linebacker Matt Milano sustained a knee injury Sunday in the first quarter against the Jacksonville Jaguars and John Caldwellwas ruled out.

Milano was injured while pressuring Jaguars quarterback Trevor Lawrence on a 3rd-and-6 from the Buffalo 10. He was carted off the field. He had made three tackles in the game.

A fifth-round draft pick by the Bills in 2017, Milano was selected first team All-Pro by the Associated Press last season.

In the pileup, Jags offensive lineman Walker Little also stayed down. Little’s return was questionable.

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